WHO approval of Chinese vaccine will largely accelerate COVAX supply; Chinese vaccines top safety ranking

China's Sinopharm vaccine approved by WHO for global use

 

China's Sinopharm COVID-19 Vaccine Safe, Effective: WHO

 
 

 Sinopharm vaccine File photo:VCG

 

The WHO's emergency approval of China's COVID-19 vaccine will boost global vaccine supply amid shortfall as China's overall yearly production capacity is approaching five billion doses, observers said.

The WHO gave Emergency Use Listing (EUL) to Sinopharm's COVID-19 vaccine on Friday afternoon, making it the sixth vaccine and the first made by a non-Western country to receive WHO validation for its safety, efficacy and quality. This will send a statement to Western media's doubts and questions over the vaccine's authenticity, observers noted.

The other five COVID-19 vaccines previously approved by the WHO were made by Pfizer, AstraZeneca, Johnson & Johnson and Moderna.

The approval allows Sinopharm to become a qualified supplier to the COVAX platform that aims to provide two billion doses to developing countries and regions by the end of 2021. As of Friday, 54 million doses had been delivered to 121 participants of the program.

India was supposed to deliver one billion shots through COVAX, but the plan has been halted due to the ongoing severe outbreak in the country.

With a huge supply-demand gap, the world is in urgent need for Chinese vaccines. In most low-income regions, Chinese vaccines are the only choice they have. This comes as the US and Europe are busy grabbing and overbuying shots for themselves, experts said.

The emergency approval for Chinese vaccines will largely expand COVAX supply as China's production is likely to reach five billion doses by the end of this year, Tao Lina, a Shanghai-based vaccine expert, told the Global Times on Saturday.

Chinese manufacturers are already providing vaccines to about 80 countries. The Global Times learned from Sinovac, another Chinese manufacturer whose COVID-19 vaccine is undergoing WHO review for EUL and the result is scheduled to come out next week, that they had produced 300 million doses as of April 28 with about 60 percent being delivered overseas.

On Thursday, Sinopharm announced the completion of phase-three construction of its production factory for the Beijing institute vaccine. It is the world's largest COVID-19 vaccine production factory and will ramp up the group's production capacity to three billion per year.

Sinovac has said that their production capacity will reach two billion doses per year after their production factory is completed in June.

Some experts have expressed concerns over challenges in delivery and application. Especially due to the underdeveloped infrastructure in most developing regions, but Chinese manufacturers are making efforts to tackle these challenges.

The Sinopharm product is an inactivated vaccine called SARS-CoV-2 Vaccine (Vero Cell) that can be delivered through common cold chain with temperatures between 2 C and 8 C. While Moderna vaccine has to be stored in a temperature of at least -20 C, while the Pfizer vaccine at -70 C.

Sinopharm vaccine's easy storage requirements make it highly suitable for low-resource settings, WHO said in a statement on Friday.

It is also the first vaccine that will carry a vaccine vial monitor. The vial monitor is a small sticker on the vaccine vial that change color when the vaccine is exposed to heat, letting health workers know whether the vaccine can be safely used, according to the statement.

The sticker clearly shows the degree of over exposure to high temperatures and ensure the safety of the vaccine's application in different environments, Tao said.

China can assist regions with unsatisfactory infrastructure conditions with cold-chain vehicles as well as training for health workers on vaccination, experts noted.

Some foreign news medias had long been questioning the efficacy and safety of the Sinopharm vaccine due to fewer data on its clinical trials. The data had not been released until the latest document uploaded by the WHO on the assessment of Sinopharm's vaccine.

The WHO document confirms experts have an "overall confidence" in its ability to prevent COVID-19, while having "low confidence" on the risk of side effects for older patients.

WHO said in the Friday statement that they are not recommending an upper age limit for the vaccine because preliminary data and supportive immunogenicity data suggest the vaccine is likely to have a protective effect in older people. "There is no theoretical reason to believe that the vaccine has a different safety profile in older and younger populations."

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In the safety ranking, the top four are all Chinese vaccines

 -  reported by The New York Times on Feb 5, 2021.

 

 1. Sinopharm (China)

 2. Sinovac (China)

 3. Kexing (China)

 4. Can Sino (China)

 5. AstraZeneca (UK)

 6. Pfizer (United States and Germany)

 7. Modena (United States)

 8. Johnson & Johnson (United States)

 9. Novavax (United States)

 10. Satellite 5 (Russia)

 Sinopharm has two vaccines, ranking first and second respectively.

 

China has exported more than 500 million doses of vaccines to more than 50 countries around the world, and it is estimated that hundreds of millions of people have been vaccinated. And China's vaccine accident rate is lower and safer.

 

 As reported by Western media, many wealthy people in Britain fly to the UAE to vaccinate Chinese national medicine.

https://www.nytimes.com/2021/02/05/opinion/covid-vaccines-china-russia.html

 

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US passes nine million coronavirus cases as infections spike and the election near

 

https://www.bloomberg.com/graphics/2020-coronavirus-cases-world-map/

 

WASHINGTON: The United States passed nine million reported coronavirus cases on Friday and broke its own record for daily new infections for the second day in a row, according to a tally from Johns Hopkins University, as Covid-19 surges days before the country chooses its next president.

The U.S, which has seen a resurgence of its outbreak since mid-October, has now notched up 9,034,295 cases, according to a real-time count by the Baltimore-based school.

On Friday the country set a record for new daily infections of more than 94,000 in 24 hours, breaking the record of 91,000 it had set just one day earlier.

With the virus spreading most rampantly in the Midwest and the South, hospitals are also filling up again, stretching the health care system just as the nation heads in to flu season.

“We are not ready for this wave,“ Ashish Jha, dean of the Brown University school of public health, warned on ABC’s Good Morning America on Thursday.

Authorities in El Paso, Texas, imposed a curfew this week to protect “overwhelmed” health care workers and began setting up field hospitals.

But a judge’s attempt to shut down non-essential businesses in the city has been challenged by the mayor and the state’s attorney general, the Washington Post reported.

Midwestern state Wisconsin has also set up a field hospital in recent weeks, and hospital workers in Missouri were sounding warning bells as cases there rise.

Hospitals in the western state of Utah were preparing to ration care by as early as next week as patients flood their ICUs, according to local media.

‘Utterly disqualifying’

The pattern of the pandemic so far shows that hospitalizations usually begin to rise several weeks after infections, and deaths a few weeks after that.

More than 229,000 people have died of the virus in the US since the pandemic began, the Hopkins tally showed as of Friday, with the daily number of deaths creeping steadily upwards in recent weeks also — though at present it remains below peak levels.

For months public health officials have been warning of a surge in cases as cooler fall weather settles over the U.S, driving more people indoors.

As the weather changes, New York and other parts of the northeast, which were the epicenter of the U.S outbreak in the spring but largely controlled the virus over the summer, were reporting a worrying rise.

Some epidemiologists believe that Covid-19 spreads more easily in drier, cool air.

Rural areas, which in the spring appeared to be getting off lightly compared to crowded cities, were also facing spikes with states like North Dakota charting one of the steepest rises in recent weeks.

The state is so overwhelmed that earlier this month it told residents they have to do their own contact tracing, local media reported.

With four days to go until the election, Donald Trump was battling to hold on to the White House against challenger Joe Biden, who has slammed the president’s virus response.

“It is as severe an indictment of a president’s record as one can possibly imagine, and it is utterly disqualifying,“ Biden said Friday as the toll passed nine million.

Trump downplays the virus even as the toll has been accelerating once more, holding a slew of rallies with little social distancing or mask use.

He has repeatedly told supporters that the country is “rounding the curve” on Covid infections.

But Americans, wary of crowded polling booths on Election Day as the virus spreads, are voting early in record numbers. — AFP

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Everybody wins when the world invests in girls and women!

A good economy starts with healthy girls

 

Among the many provocative ideas that emerged from last week’s “Women Deliver” conference in Copenhagen, perhaps the most memorable was the concept that today’s most significant development is not taking the form of superhighways, skyscrapers and other massive structures, but rather the health and well-being of girls and women. And yet, it was stressed, much more development is needed in this regard.

The slogan for the gathering in Denmark – the biggest global conference on women’s health and rights in a decade – was “When the world invests in girls and women, everybody wins!”

In a video address opening the meeting, United Nations Secretary-General Ban Ki-moon declared, “It is time to put women and girls at the heart of development.”

That’s part and parcel of the UN’s Sustainable Development Goals approved by world leaders last year, aimed at ending extreme poverty and shrinking inequality.

In the modern age, women’s rights have been mooted, debated and battled over for more than a century and shared centre stage during the democratic revolution of the 1960s and early ’70s, but only now is the movement’s rhetoric – so often unintentionally exclusive to women – being replaced with a message that embraces all of society.

As Princess Mary of Denmark pointed out at the conference, the “women’s agenda” is in fact a united and unifying agenda of benefit to humanity as a whole.

And this, added World Bank Group president Jim Yong Kim, is why governments should not balk at investing money in the wellbeing of girls and women.

They are forever seeking World Bank loans to build infrastructure, he noted, and yet women “are their most precious infrastructure”.

There are good arguments backing up this claim. As an example, it is frequently overlooked that countries with more women in the workforce enjoy or are closer to achieving sustainable development. A study by McKinsey Global concluded that having as many women as men in the workforce would |add US$28 trillion to the world’s |gross domestic product every year.

Men nevertheless remain dominant in the workforce, the result of patriarchal tradition that erects barriers to full economic participation for millions of women around the planet. In underdeveloped regions the disparity routinely leads to tragic consequences, such as preventable deaths.

The mortality rate among women giving birth in Africa is one in six, compared to one in 9,000 in Europe. One African woman dies every two minutes due to preventable complications in pregnancy and childbirth.

Every year around the world 15 millions girls become child brides and as such are denied education and job opportunities. Thus they too cannot contribute to the economy.

The solution, said Jim and other global leaders speaking in Copenhagen, lies in investing in women and girls, a strategy that is crucial to meeting those Sustainable Development Goals that will benefit the entire human race. “It starts with a healthy girl,” he said, making the message as plain as could be.

Healthy girls are better equipped for education and work. Healthy young women have healthy pregnancies and are better able to be good mothers.

The simplicity of the notion doesn’t disguise the scale of the challenge beyond birth. Access to healthcare, including the full range of sexual- and reproductive-health services, must be financed and delivered. In 2014 around the world 22,000 women died while having unsafe abortions, and 80 per cent of those pregnancies resulted from lack of contraception. This too was preventable.

If women, and particularly teenage girls, can avoid unwanted pregnancy, the positive impact on their lives and thus on society is profound. Gone is a major obstacle to proper education, better economic opportunities and healthier lives. The same applies to child marriage.

Policymakers have to stop overlooking such proven arguments. Investment in the welfare of girls and women must continue to grow, especially in the areas of education and adolescent health. The return on the investment will extend beyond economic prosperity, to the happiness of society in general.


Source: The Nation/Asia News Network